Presentations

    Laser-induced microexplosions: Ultrafast physics with clinical applications, at Physics Colloquium, Texas A&M University (College Station, TX), Thursday, February 18, 1999:
    Recently there has been much interest in using femtosecond laser pulses in surgical applications. For example, femtosecond lasers could replace the nanosecond systems currently used for opthalmic photodisruption, providing improved surgical precision and adding versatility. In surgical applications, it is the high intensity of femtosecond laser pulses that is exploited. By tightly focusing these short pulses, the intensity becomes high enough to cause nonlinear absorption inside a transparent material (such as the vitreous humor). The absorption produces a hot plasma inside the sample that is... Read more about Laser-induced microexplosions: Ultrafast physics with clinical applications
    Subcellular surgery and nanoneurosurgery, at A Year of Physics Colloquium, North Carolina A&T State University (Greensboro, NC), Thursday, November 10, 2005:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanoneurosurgery
    Subcellular surgery and nanosurgery, at Sigma Pi Sigma Colloquium, University of Connecticut (Storrs, CT), Friday, April 28, 2006:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at Physics Colloquium, University of Massachusetts Lowell (Lowell, MA), Wednesday, April 25, 2007:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at Physics Colloquium, Amherst College (Amherst, MA), Thursday, October 4, 2007:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at Physics Colloquium, University of British Columbia (Vancouver, BC, Canada), Friday, October 19, 2007:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at Physics Colloquium, University of Kentucky (Lexington, KY), Thursday, October 25, 2007:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at Baetjer Colloquium, Princeton University (Princeton, NJ), Friday, November 16, 2007:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Femtosecond laser interactions with materials: from micromachining to microsurgery, at Materials Science and Engineering Colloquium, Stanford University (Palo Alto, CA), Friday, October 31, 2008:
    When femtosecond laser pulses are focused tightly into a transparent material, the intensity in the focal volume can become high enough to cause nonlinear absorption of laser energy. The absorption, in turn, can lead to permanent structural or chemical changes. Such changes can be used for micromachining bulk transparent materials. Applications include data storage and the writing of waveguides and waveguide splitters in bulk glass, and fabrication of micromechanical devices in polymers.

    We have used this technique to manipulate sub-cellular structures inside live and fixed cells. Using...

    Read more about Femtosecond laser interactions with materials: from micromachining to microsurgery
    Subcellular surgery and nanosurgery, at Physics Colloquium, University of Massachusetts Boston (Boston, MA), Wednesday, November 5, 2008:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at Physics Colloquium, Australian National University (Canberra, Australia), Tuesday, March 24, 2009:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at Physics Colloquium, Clark University (Worcester, MA), Wednesday, April 7, 2010:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at Physics Colloquium, University of Notre Dame (Notre Dame, IN), Wednesday, May 12, 2010:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at Special Laser Seminar / NCCR MUST Seminar, ETH Zürich (Zürich, Switzerland), Thursday, February 23, 2012:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at Neils Colloquium for Innovative Science, Valparaiso University (Valparaiso, IN), Friday, November 1, 2013:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at Biophysics Colloquium, Elon University (Elon, NC), Friday, October 16, 2015:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at Chemistry Seminar, Middle Tennessee University, Friday, February 12, 2021

    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual...

    Read more about Subcellular surgery and nanosurgery