Presentations

    Laser-induced microexplosions: ultrafast physics with clinical applications, at 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Hong Kong), Thursday, October 29, 1998:
    We used water and human skin tissue to compare the surgical potential of 100-fs and 200-ps laser pulses. For investigation of threshold behavior of 100-fs and 200-ps pulses, we use water as a model for tissue. In addition to having a lower threshold, we find that energy deposition is much more consistent with 100-fs pulses. We also compared 100-fs and 200-ps laser pulse effects on the surface and in the bulk of human skin tissue. On the surface, pulses with 100-fs and 200-ps duration leave similar size ablation regions. In the bulk both 100-fs and 200-ps pulses produce cavities, however, 100-... Read more about Laser-induced microexplosions: ultrafast physics with clinical applications
    Subcellular surgery and nanosurgery, at CIMIT/Lester Wolfe Workshop on Femtosecond Microscopy & Microsurgery, Wellman Center for Photomedicine (Boston, MA), Tuesday, April 18, 2006:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanosurgery
    Subcellular surgery and nanosurgery, at CLEO 2007 (Baltimore, MD), Thursday, May 10, 2007:
    We use femtosecond laser pulses to probe the mechanical propertiesof the actin network in live cells and to probe cell regeneration and the neurological basis of behavior in C. elegans.
    Nanosurgery with Femtosecond Lasers, at 2009 OSA Frontiers in Optics (San Jose, CA), Wednesday, October 14, 2009:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Nanosurgery with Femtosecond Lasers
    Subcellular surgery and nanoneurosurgery, at 36th Winter Colloquium on The Physics of Quantum Electronics (Snowbird, UT), Wednesday, January 4, 2006:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Subcellular surgery and nanoneurosurgery
    Using short bursts of photons to manipulate biological matter at the nanoscale, at Winter Colloquium on the Physics of Quantum Electronics (Snowbird, UT), Friday, January 5, 2007:
    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the function of individual... Read more about Using short bursts of photons to manipulate biological matter at the nanoscale
    Subcellular surgery and nanoneurosurgery, at CLEO-PR 2017 in Singapore, Thursday, August 3, 2017

     

    We use femtosecond laser pulses to manipulate sub-cellular structures inside live and fixed cells. Using only a few nanojoules of laser pulse energy, we are able to selectively disrupt individual mitochondria in live bovine capillary epithelial cells, and cleave single actin fibers in the cell cytoskeleton network of fixed human fibro-blast cells. We have also used the technique to micromanipulate the neural network of C. Elegans, a small nematode. Our laser scalpel can snip individual axons without causing any damage to surrounding tissue, allowing us to study the...

    Read more about Subcellular surgery and nanoneurosurgery