@article {Chung:712,
	title = {Femtosecond Laser Ablation Reveals Antagonistic Sensory and Neuroendocrine Signaling that Underlie C. elegans Behavior and Development},
	journal = {Cell Reports},
	volume = {4},
	year = {2013},
	pages = {316{\textendash}326},
	abstract = {The specific roles of neuronal subcellular compo- nents in behavior and development remain largely unknown, even though advances in molecular biology and conventional whole-cell laser ablation have greatly accelerated the identification of contrib- utors at the molecular and cellular levels. We system- atically applied femtosecond laser ablation, which has submicrometer resolution in vivo, to dissect the cell bodies, dendrites, or axons of a sensory neuron (ASJ) in Caenorhabditis elegans to determine their roles in modulating locomotion and the develop- mental decisions for dauer, a facultative, stress- resistant life stage. Our results indicate that the cell body sends out axonally mediated and hormonal sig- nals in order to mediate these functions. Further- more, our results suggest that antagonistic sensory dendritic signals primarily drive and switch polarity between the decisions to enter and exit dauer. Thus, the improved resolution of femtosecond laser ablation reveals a rich complexity of neuronal signaling at the subcellular level, including multiple neurite and hormonally mediated pathways depen- dent on life stage.},
	doi = {10.1016/j.celrep.2013.06.027},
	url = {/files/mazur/files/rep_712.pdf},
	author = {S. H. Chung and A. Schmalz and R. Clarissa Ruiz and C. V. Gabel and Mazur, E.}
}
