%0 Journal Article %J Langmuir %D 2009 %T Femtosecond laser-nanostructured substrates for surface-enhanced Raman scattering %A E. D. Diebold %A N. H. Mack %A S. K. Doorn %A Mazur, E. %X We present a new type of surface-enhanced Raman scattering (SERS) substrate that exhibits extremely large and uniform cross-section enhancements over a macroscopic (greater than 25 mm2) area. The substrates are fabricated using a femtosecond laser nanostructuring process, followed by thermal deposition of silver. SERS signals from adsorbed molecules show a spatially uniform enhancement factor of approximately 107. Spectroscopic characterization of these substrates suggests their potential for use in few or single-molecule Raman spectroscopy. %B Langmuir %V 25 %P 1790–1794 %G eng %U /files/mazur/files/rep_616.pdf %R 10.1021/la803357q